A surprisingly stable S-nitrosothiol complex

Laura L Perissinotti; Darío A Estrin; Gregory Leitus; Fabio Doctorovich

doi:10.1021/ja0565976

A surprisingly stable S-nitrosothiol complex

J Am Chem Soc. 2006 Mar 1;128(8):2512-3. doi: 10.1021/ja0565976.

Authors

Laura L Perissinotti¹, Darío A Estrin, Gregory Leitus, Fabio Doctorovich

Affiliation

¹ Departamento de Química Inorgánica, Analítica y Química Física/INQUIMAE-CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, Argentina.

PMID: 16492016
DOI: 10.1021/ja0565976

Abstract

In this work we present for the first time an X-ray structure of a coordinated S-nitrosothiol obtained by reaction of the extremely reactive K[IrCl5NO] with benzylmercaptan in acetonitrile. This surprisingly stable compound, trans-K[IrCl4(CH3CN)N(O)SCH2Ph], was isolated in high yield (80%) and fully characterized by FTIR, 1H NMR, and ESI-MS. To our knowledge this is the first example of a coordinated S-nitrosothiol that has been isolated.