A one-step synthesis and antimicrobial activities of new substituted dihydro-1,3,4-thiadiazoles

Abstract

In this study, 2-N-arylimino-2,3-dihydro-1,3,4-thiadiazoles derivatives (6a-h) were synthetized. The mechanism of the studied reactions was discussed. The chemical structures of the compounds were elucidated by their IR, 1H-NMR, 13C-NMR, and Mass spectral data and elemental analyses. The compounds were tested for antimicrobial activity using diffusion agar technique.