QSAR study of mosquito repellents using Codessa Pro

Alan R Katritzky; Dimitar A Dobchev; Indrek Tulp; Mati Karelson; David A Carlson

doi:10.1016/j.bmcl.2005.11.113

QSAR study of mosquito repellents using Codessa Pro

Bioorg Med Chem Lett. 2006 Apr 15;16(8):2306-11. doi: 10.1016/j.bmcl.2005.11.113. Epub 2006 Feb 20.

Authors

Alan R Katritzky¹, Dimitar A Dobchev, Indrek Tulp, Mati Karelson, David A Carlson

Affiliation

¹ Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL 32611, USA. katritzky@chem.ufl.edu

PMID: 16488605
DOI: 10.1016/j.bmcl.2005.11.113

Abstract

Protection times provided by 31 synthetic repellents against Aedes aegypti mosquitoes were correlated with the chemical structures of these repellents using Codessa Pro software. Two statistically significant quantitative models with R2 values of ca. 0.80 are presented and discussed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Bites and Stings / prevention & control*
Culicidae / drug effects*
Insect Repellents / pharmacology*
Insect Repellents / therapeutic use
Quantitative Structure-Activity Relationship
Software*

Substances

Insect Repellents