Effective asymmetric epoxidation of styrenes by chiral dioxirane

David Goeddel; Lianhe Shu; Yi Yuan; O Andrea Wong; Bin Wang; Yian Shi

doi:10.1021/jo0520285

Effective asymmetric epoxidation of styrenes by chiral dioxirane

J Org Chem. 2006 Feb 17;71(4):1715-7. doi: 10.1021/jo0520285.

Authors

David Goeddel¹, Lianhe Shu, Yi Yuan, O Andrea Wong, Bin Wang, Yian Shi

Affiliation

¹ Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.

PMID: 16468831
DOI: 10.1021/jo0520285

Abstract

High enantioselectivity (80-92% enantiomeric excess (ee)) has been obtained for the epoxidation of various styrenes using an easily prepared ketone (4) catalyst.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Epoxy Compounds / chemistry*
Ketones / chemistry
Stereoisomerism
Styrenes / chemical synthesis*
Styrenes / chemistry

Substances

Epoxy Compounds
Ketones
Styrenes
dioxirane

Grants and funding

GM59705-06/GM/NIGMS NIH HHS/United States