Abstract
Lichenicolous fungus LL-RB0668 was isolated from a processed lichen thallus on a modified Lilly-Barnett solid medium. Two new bisnaphthopyrone compounds, lichenicolins A (1) and B (2), were isolated from the culture broth of this organism fermented on a rice-based solid medium. These results demonstrate that lichen-associated fungi potentially are a good resource for new bioactive natural products for current screening programs.
MeSH terms
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Anti-Bacterial Agents / chemistry*
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology*
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Antifungal Agents / chemistry
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Antifungal Agents / isolation & purification
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Antifungal Agents / pharmacology
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Candida albicans / drug effects
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Culture Media / chemistry
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Fermentation
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Fungi / isolation & purification
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Fungi / metabolism*
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Gram-Negative Bacteria / drug effects
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Gram-Positive Bacteria / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Molecular Structure
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Pyrones / chemistry*
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Pyrones / isolation & purification
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Pyrones / pharmacology*
Substances
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Anti-Bacterial Agents
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Antifungal Agents
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Culture Media
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Pyrones