Lichenicolins A and B, new bisnaphthopyrones from an unidentified lichenicolous fungus, strain LL-RB0668

J Antibiot (Tokyo). 2005 Nov;58(11):731-6. doi: 10.1038/ja.2005.99.

Abstract

Lichenicolous fungus LL-RB0668 was isolated from a processed lichen thallus on a modified Lilly-Barnett solid medium. Two new bisnaphthopyrone compounds, lichenicolins A (1) and B (2), were isolated from the culture broth of this organism fermented on a rice-based solid medium. These results demonstrate that lichen-associated fungi potentially are a good resource for new bioactive natural products for current screening programs.

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology
  • Candida albicans / drug effects
  • Culture Media / chemistry
  • Fermentation
  • Fungi / isolation & purification
  • Fungi / metabolism*
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Pyrones / chemistry*
  • Pyrones / isolation & purification
  • Pyrones / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Culture Media
  • Pyrones