A strategy for constructing a hybrid bilayer membrane based on a carbon substrate

Xiaojun Han; Li Wang; Bin Qi; Xiurong Yang; Erkang Wang

doi:10.1021/ac034592q

A strategy for constructing a hybrid bilayer membrane based on a carbon substrate

Anal Chem. 2003 Dec 1;75(23):6566-70. doi: 10.1021/ac034592q.

Authors

Xiaojun Han¹, Li Wang, Bin Qi, Xiurong Yang, Erkang Wang

Affiliation

¹ State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.

PMID: 16465708
DOI: 10.1021/ac034592q

Abstract

We construct a hybrid bilayer membrane (HBM) on a new substrate-carbon electrode. It is an extension of HBM based on other substrates. Primary alkylamine was chemically modified onto the surface of a carbon electrode by electrochemical scans; thus, a monolayer was formed on the electrode. Because the alkane chains section is toward the outside, a hydrophobic surface was constructed. Then a lipid monolayer was spread on the hydrophobic surface of the carbon electrode. The formed HBM was characterized by electrochemical and ATR-FT-IR methods. From ATR-FT-IR results, the lipid order parameter (S) of 0.73 was obtained. This kind of hybrid membrane has the advantages of a lipid/alkanethiol HBM. A potential application of this HBM as a biosensor (detecting K+) was given.