[Pharmacological characteristics and clinical efficacy of bosentan]

MeSH terms

• Animals
• Antihypertensive Agents / adverse effects
• Antihypertensive Agents / pharmacology*
• Antihypertensive Agents / therapeutic use*
• Bosentan
• Disease Models, Animal
• Drug-Related Side Effects and Adverse Reactions
• Endothelin A Receptor Antagonists
• Endothelin B Receptor Antagonists
• Endothelin-1 / antagonists & inhibitors
• Endothelin-1 / physiology
• Humans
• Hypertension, Pulmonary / drug therapy*
• Hypertension, Pulmonary / prevention & control
• In Vitro Techniques
• Nitric Oxide Synthase / antagonists & inhibitors
• Randomized Controlled Trials as Topic
• Sulfonamides / adverse effects
• Sulfonamides / pharmacology*
• Sulfonamides / therapeutic use*
• Vasoconstriction / drug effects