CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38- counter-parts

Leukemia. 2006 Apr;20(4):743-4. doi: 10.1038/sj.leu.2404133.

Authors

C Pepper, P Brennan, S Alghazal, R Ward, G Pratt, J Starczynski, T Lin, C Rowntree, C Fegan

PMID: 16452999
DOI: 10.1038/sj.leu.2404133

No abstract available

Publication types

Comparative Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

ADP-ribosyl Cyclase 1 / biosynthesis
ADP-ribosyl Cyclase 1 / genetics*
B-Lymphocytes / pathology*
Flow Cytometry
Gene Expression Regulation, Leukemic*
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Leukemia, Lymphocytic, Chronic, B-Cell / metabolism
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Lymphocyte Count
Signal Transduction
ZAP-70 Protein-Tyrosine Kinase / biosynthesis
ZAP-70 Protein-Tyrosine Kinase / genetics*

Substances

ZAP-70 Protein-Tyrosine Kinase
ZAP70 protein, human
ADP-ribosyl Cyclase 1