Emergence of Enterobacteriaceae isolates producing CTX-M extended-spectrum beta-lactamase in Austria

Antimicrob Agents Chemother. 2006 Feb;50(2):785-7. doi: 10.1128/AAC.50.2.785-787.2006.

Abstract

Among 149 extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolates collected from patients in southeast Austria from 1998 to 2004, 38 Escherichia coli isolates and 11 Klebsiella spp. were CTX-M producers. The proportion of CTX-M-producers among all ESBL producers rose from 0% in 1998 to 58% in 2004. In general, CTX-M-producers had heterogeneous pulsed-field gel electrophoresis patterns, but one E. coli isolate was identical to a United Kingdom epidemic CTX-M-15-producing strain, although no epidemiological link with the United Kingdom was apparent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electrophoresis, Gel, Pulsed-Field
  • Enterobacteriaceae / drug effects
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / genetics
  • Escherichia coli Proteins / biosynthesis
  • Humans
  • beta-Lactamases / biosynthesis*

Substances

  • Escherichia coli Proteins
  • CTX-M-9 protein, E coli
  • beta-lactamase CTX-2
  • beta-lactamase CTX-M-15
  • beta-lactamase TEM-3
  • beta-Lactamases