We report here the first case of isolated uterine endometrial sarcoidosis presenting as an asymptomatic polypoid lesion. A 52-year-old patient, who had her last menstrual period 2 years before, was submitted to an office hysteroscopy because of an ultrasonographic finding of endometrial thickening preceding hormonal therapy. A polypoid endometrial lesion removed by surgical hysteroscopy revealed chronic granulomatous endometritis. After excluding other granulomatous diseases, the diagnose of sarcoidosis was corroborated. The finding of polypoid endometrial sarcoidosis expands the differential diagnoses possibilities in case of endometrial polyps.