Intramedullary spinal tuberculoma: report of three cases

Surg Neurol. 2006 Feb;65(2):185-8; discussion 188-9. doi: 10.1016/j.surneu.2005.05.026.

Abstract

Background: Intramedullary spinal tuberculoma is a rare form of central nervous system tuberculosis. This article describes the successful management of intramedullary spinal tuberculoma in 3 patients who received treatment between 2000 and 2003.

Case description: The character of 3 cases was analyzed retrospectively, including clinical manifestation and magnetic resonance imaging findings. All masses were excised totally under microscope. Histopathologic examination revealed tuberculoma. Postoperatively, all patients received a 6 to 9 month course of ATT. The outcome was favorable.

Conclusions: The intramedullary spinal tuberculoma must be considered in the differential diagnosis of the spinal cord compression in patients with a history of tuberculosis. When confronted with a progressing neurologic deficit and poor response to ATT, surgical intervention should be considered. The optimal treatment is a combination of microsurgical resection and ATT.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Spinal Cord / microbiology
  • Spinal Cord / pathology*
  • Thoracic Vertebrae
  • Tuberculoma / pathology*
  • Tuberculosis, Spinal / pathology*