Choroidal detachment after topical prostaglandin analogs: case report

J Med Assoc Thai. 2005 Aug;88(8):1134-6.

Abstract

Objective: To report three cases of delayed choroidal detachment after treatment with topical prostaglandin analogs.

Material and method: Intervention three case reports. Four eyes of three patients with chronic angle closure glaucoma developed choroidal detachment after using topical prostaglandin analogs.

Results: Three patients with chronic angle closure glaucoma developed chroidal detachment in one week, three weeks and two years after using travoprost, bimatoprost and latanoprost respectively. All of them resolved after discontinuation of these medications. All of the eyes that developed chroidal detachment were pseudophakic.

Conclusion: Travoprost, bimatoprost and latanoprost may lead to choroidal detachment and hypotony. Pseudophakic patients may be at high risk of the development of chroidal detachment. Topical prostaglandin analogs should be used cautiously in these patients.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Aged
  • Amides
  • Bimatoprost
  • Choroid Diseases / chemically induced*
  • Cloprostenol / adverse effects
  • Cloprostenol / analogs & derivatives
  • Female
  • Glaucoma, Angle-Closure / drug therapy*
  • Humans
  • Latanoprost
  • Lipids / adverse effects
  • Middle Aged
  • Ocular Hypotension
  • Prostaglandins F, Synthetic / adverse effects
  • Prostaglandins, Synthetic / adverse effects*
  • Risk Factors
  • Time Factors
  • Travoprost

Substances

  • Amides
  • Lipids
  • Prostaglandins F, Synthetic
  • Prostaglandins, Synthetic
  • Cloprostenol
  • Latanoprost
  • Bimatoprost
  • Travoprost