OPM: orientations of proteins in membranes database

Bioinformatics. 2006 Mar 1;22(5):623-5. doi: 10.1093/bioinformatics/btk023. Epub 2006 Jan 5.

Abstract

Summary: The Orientations of Proteins in Membranes (OPM) database provides a collection of transmembrane, monotopic and peripheral proteins from the Protein Data Bank whose spatial arrangements in the lipid bilayer have been calculated theoretically and compared with experimental data. The database allows analysis, sorting and searching of membrane proteins based on their structural classification, species, destination membrane, numbers of transmembrane segments and subunits, numbers of secondary structures and the calculated hydrophobic thickness or tilt angle with respect to the bilayer normal. All coordinate files with the calculated membrane boundaries are available for downloading.

Availability: http://opm.phar.umich.edu.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Graphics
  • Computer Simulation
  • Databases, Protein*
  • Membrane Proteins / chemistry*
  • Membrane Proteins / classification
  • Models, Chemical*
  • Models, Molecular*
  • Protein Conformation
  • Proteins / chemistry*
  • Proteins / classification*
  • Sequence Analysis, Protein / methods*
  • User-Computer Interface

Substances

  • Membrane Proteins
  • Proteins