Abstract
Cardiovascular disease and major depression are highly prevalent disorders in our society. Evidence has been found that confirms a reciprocal relationship between mechanisms of depression and those of cardiovascular pathology. This possible feedback between both pathologies is a subject of great concern. In recent years some studies suggest that platelets and serotonergic mechanisms could be involved in both conditions. The present review seeks a better understanding of the mechanisms that could link depression with an enhanced cardiovascular risk.
Copyright (c) 2005 Prous Science. All rights reserved.
MeSH terms
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Antidepressive Agents / therapeutic use
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Cardiovascular Diseases / etiology*
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Cardiovascular Diseases / metabolism
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Cardiovascular Diseases / pathology
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Clinical Trials as Topic
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Depressive Disorder / complications
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Depressive Disorder / drug therapy
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Depressive Disorder / metabolism
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Humans
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Mood Disorders / complications*
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Mood Disorders / drug therapy
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Mood Disorders / metabolism
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Receptors, Serotonin / physiology
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Selective Serotonin Reuptake Inhibitors / therapeutic use
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Serotonin / metabolism
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Serotonin / physiology*
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Serotonin Antagonists / therapeutic use
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Serotonin Plasma Membrane Transport Proteins / physiology
Substances
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Antidepressive Agents
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Receptors, Serotonin
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Serotonin Antagonists
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Serotonin Plasma Membrane Transport Proteins
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Serotonin Uptake Inhibitors
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Serotonin