A mixture of five new ceramides was isolated from the aerial parts of Rantherium suaveolens and characterized by spectroscopic and chemical methods. Their structures were elucidated by spectroscopic and chemical methods as (2S,3S, 4R,2'R, 14E)-2-(2'-hydroxydocosanoylamino) - 14 - octadecene -1,3,4-triol (1), (2S,3S,4R,2'R, 14E)-2-(2'-hydroxytricosanoylamino)-14-octadecene-1,3,4-triol (2), (2S,3S,4R,2'R, 14E)-2-(2'-hydroxytetracosanoylamino)- 14 - octadecene - 1,3,4 - triol (3), (2S, 3S,4R,2'R, 14E) - 2 - (2'- hydroxypentacosanoylamino) - 14 - octadecene - 1,3,4-triol (4), and (2S,3S,4R,2'R,14E)-2-(2'-hydroxyhexacosanoylamino)-14-octadecene-1,3,4-triol (5).