To efficiently protect the endangered traditional Chinese medicine herbs is essential for the sustainable development of traditional Chinese medicine. On the bases of present species endanger and protection levels, problems in the traditional Chinese medicine herbs are analyzed. The endangered levels of traditional Chinese medicine herbs should refer to the standard of IUCN, and the protection levels should adopt qualitative and quantitative analysis based on the characteristic of traditional Chinese medicine herbs. Some qualitative and quantitative factors are discussed, some useful information was also provided for the establishment of protection levels of traditional Chinese medicine herbs.