Abstract
A novel plasmid-mediated metallo-beta-lactamase (IMP-9) is described in seven isolates of Pseudomonas aeruginosa from Guangzhou, China, isolated in 2000. The gene was carried on a large (approximately 450-kb) IncP-2 conjugative plasmid. This is the first report of carriage of bla(IMP) genes on such large plasmids.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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China
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Conjugation, Genetic
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Drug Resistance, Multiple, Bacterial*
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Humans
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Microbial Sensitivity Tests
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Plasmids / genetics*
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Pseudomonas Infections / microbiology
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Pseudomonas aeruginosa / drug effects
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Pseudomonas aeruginosa / enzymology*
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Pseudomonas aeruginosa / genetics*
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Pseudomonas aeruginosa / isolation & purification
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beta-Lactamases / genetics
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beta-Lactamases / metabolism*