Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen

Per Klemm; Viktoria Roos; Glen C Ulett; Catharina Svanborg; Mark A Schembri

doi:10.1128/IAI.74.1.781-785.2006

Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen

Infect Immun. 2006 Jan;74(1):781-5. doi: 10.1128/IAI.74.1.781-785.2006.

Authors

Per Klemm¹, Viktoria Roos, Glen C Ulett, Catharina Svanborg, Mark A Schembri

Affiliation

¹ School of Molecular and Microbial Sciences, Building 76, University of Queensland, Brisbane QLD 4072, Australia.

Abstract

Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Bacteriuria / metabolism
Bacteriuria / microbiology*
Escherichia coli / genetics*
Escherichia coli / pathogenicity*
Escherichia coli / ultrastructure
Escherichia coli Infections / metabolism
Escherichia coli Infections / microbiology*
Fimbriae, Bacterial / genetics
Fimbriae, Bacterial / ultrastructure
Humans
Molecular Sequence Data