A polydiacetylene-based fluorescent sensor chip

J Am Chem Soc. 2005 Dec 21;127(50):17580-1. doi: 10.1021/ja0547275.

Abstract

Self-assembled diacetylene vesicles were spotted and immobilized on aldehyde-modified glass substrates using conventional microarray technology. Irradiation of the immobilized diacetylenes allowed generation of nonfluorescent "blue-phase" polydiacetylene (PDA) arrays. Specific interaction of the PDA vesicle arrays with carbohydrates or poly(acrylic acid) solutions afforded fluorescent profiles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylene / analogs & derivatives*
  • Acetylene / chemistry
  • Fatty Acids, Unsaturated / chemistry
  • Fluorescent Dyes / chemistry*
  • Microscopy, Fluorescence
  • Polyacetylene Polymer
  • Polymers / chemistry*
  • Polyynes
  • alpha-Cyclodextrins / chemistry

Substances

  • 10, 12-pentacosadiynoic acid
  • Fatty Acids, Unsaturated
  • Fluorescent Dyes
  • Polyacetylene Polymer
  • Polymers
  • alpha-Cyclodextrins
  • Polyynes
  • polydiacetylene
  • Acetylene