Abstract
Stress reactions develop in different organs as a result of the effect of unfavourable factors which increase the differential threshold for men. These derangements mainly occur in the organs where we can observe an inadequacy between high level of metabolism in the cell and instability of energy supply. Under such conditions stress reactions in the cells have the following stages in succession: intensiveness of the lipolysis in mitochondria, accumulation in the cells of fatty acid metabolites, destruction of the membranous apparatus of the cells, increase in the presence of Ca++ in the cells.
MeSH terms
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Animals
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Calcium / metabolism
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Calcium Channel Blockers / administration & dosage
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Calcium Channel Blockers / therapeutic use*
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Cardiovascular Agents / administration & dosage
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Cardiovascular Agents / therapeutic use*
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Drug Therapy, Combination
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Fatty Acids / metabolism
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Hearing Loss, Sensorineural / drug therapy
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Hearing Loss, Sensorineural / etiology
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Hearing Loss, Sensorineural / metabolism
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Humans
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Labyrinth Diseases / drug therapy*
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Labyrinth Diseases / metabolism*
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Lipolysis
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Methylhydrazines / administration & dosage
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Methylhydrazines / therapeutic use*
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Mitochondria / metabolism
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Rabbits
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Time Factors
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Vitamins / therapeutic use
Substances
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Calcium Channel Blockers
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Cardiovascular Agents
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Fatty Acids
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Methylhydrazines
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Vitamins
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3-(2,2,2-trimethylhydrazine)propionate
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Calcium