Abstract
Bioassay-guided fractionation of different extracts of both stem and stem bark of Stereospermum personatum led to the isolation of free-radical-scavenging and xanthine oxidase inhibitory molecules along with three new anthraquinones, sterequinones F-H (1-3), a new naphthoquinone, sterequinone I (4), two new phenethyl esters, 2(4'-hydroxyphenyl)ethyl undecanoate (14) and 2(4'-hydroxyphenyl)ethyl nonacosanoate (15), and a new 3,4,5-trimethoxycinnamyl ether, 2-methoxy-4-[3'-(3'',4'',5''trimethoxyphenyl)allyloxymethyl]phenol (16), together with known compounds. The antioxidant and xanthine oxidase inhibitory potentials of the isolated compounds are reported.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anthraquinones / chemistry
-
Anthraquinones / isolation & purification
-
Anthraquinones / pharmacology*
-
Antioxidants / chemistry
-
Antioxidants / isolation & purification
-
Antioxidants / pharmacology*
-
Bignoniaceae / chemistry*
-
Enzyme Inhibitors / chemistry
-
Enzyme Inhibitors / isolation & purification
-
Enzyme Inhibitors / pharmacology*
-
Free Radical Scavengers / chemistry
-
Free Radical Scavengers / isolation & purification
-
Free Radical Scavengers / pharmacology*
-
India
-
Medicine, Ayurvedic
-
Molecular Structure
-
Naphthoquinones / chemistry
-
Naphthoquinones / isolation & purification
-
Naphthoquinones / pharmacology*
-
Plant Bark / chemistry
-
Plants, Medicinal / chemistry*
-
Xanthine Oxidase / antagonists & inhibitors*
Substances
-
Anthraquinones
-
Antioxidants
-
Enzyme Inhibitors
-
Free Radical Scavengers
-
Naphthoquinones
-
sterequinone F
-
sterequinone G
-
sterequinone H
-
sterequinone I
-
Xanthine Oxidase