Polymer nano- and microspheres with bumpy and chain-segregated surfaces

J Am Chem Soc. 2005 Nov 9;127(44):15358-9. doi: 10.1021/ja054937h.

Abstract

Reported is a novel and simple method for the preparation of polymer spheres bearing hemispherical surface bumps where one type of polymer chains concentrates. The method is used to produce spheres with a diameter between approximately 30 and approximately 500 nm. Spheres with chain-segregated bumpy surfaces may find applications in drug delivery and other areas.