Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate

Anna Stojakowska; Bogdan Kedzia; Wanda Kisiel

doi:10.1016/j.fitote.2005.05.003

Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate

Fitoterapia. 2005 Dec;76(7-8):687-90. doi: 10.1016/j.fitote.2005.05.003. Epub 2005 Oct 19.

Authors

Anna Stojakowska¹, Bogdan Kedzia, Wanda Kisiel

Affiliation

¹ Department of Phytochemistry, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Kraków, Poland. stoja@if-pan.krakow.pl

PMID: 16242268
DOI: 10.1016/j.fitote.2005.05.003

Abstract

10-Isobutyryloxy-8,9-epoxythymol isobutyrate was found to be a major constituent of Inula helenium and Inula royleana root cultures. The compound showed moderate antimicrobial activity against Staphylococcus aureus, Enterococcus faecalis, Escherischia coli, Pseudomonas aeruginosa and Candida albicans.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Infective Agents / isolation & purification
Anti-Infective Agents / pharmacology*
Butyrates / isolation & purification
Butyrates / pharmacology*
Candida albicans / drug effects
Escherichia coli / drug effects
Gram-Positive Cocci / drug effects
Inula / chemistry*
Microbial Sensitivity Tests
Plant Roots / chemistry
Pseudomonas aeruginosa / drug effects
Thymol / analogs & derivatives*
Thymol / isolation & purification
Thymol / pharmacology
Tissue Culture Techniques

Substances

10-isobutyryloxy-8,9-epoxythymol isobutyrate
Anti-Infective Agents
Butyrates
Thymol