Preservative-free nasal drug-delivery systems

Med Device Technol. 2004 Nov;15(9):14-6, 18.

Abstract

Unpreserved nasal sprays are the latest trend in nasal drug delivery. Different technologies are discussed here in the context of mechanically protected systems, which may provide additional benefits. New test protocols are suggested to evaluate the improved microbiological protection that can be achieved.

MeSH terms

  • Administration, Intranasal
  • Aerosols / administration & dosage*
  • Aerosols / therapeutic use*
  • Disposable Equipment*
  • Drug Delivery Systems / instrumentation*
  • Drug Delivery Systems / methods
  • Equipment Contamination / prevention & control
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Nebulizers and Vaporizers*
  • Preservatives, Pharmaceutical

Substances

  • Aerosols
  • Preservatives, Pharmaceutical