Abstract
Various mechanisms have been proposed to explain mutually exclusive splicing of pairs of exons. A paper in this issue of Cell (Graveley, 2005) provides a fascinating insight into the perplexing question of how only one exon at a time is chosen from an array of 48 exons in the Drosophila Dscam gene.
MeSH terms
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Alternative Splicing / genetics*
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Animals
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Cell Adhesion Molecules
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Drosophila Proteins / biosynthesis
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Drosophila Proteins / genetics*
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Drosophila melanogaster / genetics*
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Exons / genetics*
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Gene Expression Regulation / genetics*
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Humans
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RNA Splice Sites / genetics
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Spliceosomes / genetics
Substances
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Cell Adhesion Molecules
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Drosophila Proteins
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Dscam1 protein, Drosophila
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RNA Splice Sites
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RNA, Messenger