Enantioselective reduction of C=N double bond by chromium(II) complexes of natural amino acids

Chirality. 2005 Nov;17(9):511-4. doi: 10.1002/chir.20193.

Abstract

Asymmetric reduction of oximes was performed by chromium(II) complexes of natural amino acids in aqueous phase or in H(2)O/DMF (1:1) solvent. Medium-to-quantitative chemoselectivity (54% to >95%) and low-to-medium enantioselectivity (5-50% ee) were found.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemistry*
  • Carbon / chemistry*
  • Chromium / chemistry*
  • Molecular Structure
  • Nitrogen / chemistry*
  • Oxidation-Reduction
  • Oximes / chemistry
  • Spectrum Analysis
  • Stereoisomerism

Substances

  • Amino Acids
  • Oximes
  • Chromium
  • Carbon
  • Nitrogen