Abstract
We identified five genes encoding components of the TOR signaling pathway within Aspergillus nidulans. Unlike the situation in Saccharomyces cerevisiae, there is only a single Tor kinase, as in plant and animal systems, and mutant phenotypes suggest that the TOR pathway plays only a minor role in regulating nitrogen metabolism.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Antifungal Agents / pharmacology
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Aspergillus nidulans / genetics*
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Aspergillus nidulans / growth & development
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Aspergillus nidulans / metabolism
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Drug Resistance, Fungal
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Fungal Proteins / genetics*
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Fungal Proteins / metabolism*
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Gene Expression Regulation, Fungal
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Molecular Sequence Data
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Mutation / genetics*
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Nitrogen / metabolism
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Phenotype
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Protein Kinases / genetics
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Protein Kinases / metabolism*
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Sequence Homology, Amino Acid
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Signal Transduction*
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Sirolimus / pharmacology
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TOR Serine-Threonine Kinases
Substances
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Antifungal Agents
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Fungal Proteins
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RNA, Messenger
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Protein Kinases
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TOR Serine-Threonine Kinases
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Nitrogen
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Sirolimus
Associated data
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GENBANK/AJ717400
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GENBANK/AJ717401
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GENBANK/AJ717402
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GENBANK/AJ717403
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GENBANK/AJ717404