Abstract
Our understanding of adult epidermal stem cells has increased substantially over the last two decades especially; however even more detailed knowledge is imperative for realizing potential medical therapies. We need to know how to identify these cells and what regulates their function. In this review, we describe the literature to date and elucidate the clinical relevance of these findings.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Aging
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Animals
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Bromodeoxyuridine / pharmacology
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Cell Differentiation
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Cell Separation
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Cells, Cultured
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Epidermal Cells*
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Epidermis / pathology
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Epithelial Cells / cytology*
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Flow Cytometry
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Humans
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Keratinocytes / metabolism
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Models, Biological
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Skin / pathology
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Stem Cell Transplantation / methods*
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Stem Cells / cytology*
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Stem Cells / metabolism