Use of paired serum samples for serodiagnosis of typhoid fever

J Clin Microbiol. 2005 Sep;43(9):4889-90. doi: 10.1128/JCM.43.9.4889-4890.2005.

Abstract

Using an enzyme-linked immunosorbent assay we demonstrate that, in adult patients with typhoid fever, the sensitivity of a serological test based on the detection of anti-lipopolysaccharide immunoglobulin G is increased when used with paired serum samples taken 1 week apart.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Bacterial / blood*
  • Antigens, Bacterial / immunology
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Immunoglobulin G / blood*
  • Lipopolysaccharides / immunology*
  • Salmonella typhi / immunology
  • Serologic Tests
  • Time Factors
  • Typhoid Fever / diagnosis*
  • Typhoid Fever / immunology
  • Typhoid Fever / microbiology

Substances

  • Antibodies, Bacterial
  • Antigens, Bacterial
  • Immunoglobulin G
  • Lipopolysaccharides