[An orbital metastasis as the presentation of lung adenocarcinoma]

Arch Soc Esp Oftalmol. 2005 Aug;80(8):467-70. doi: 10.4321/s0365-66912005000800008.
[Article in Spanish]

Abstract

Introduction: Metastasis of primary tumours can involve the orbit via the blood stream. In 19% of cases this type of metastasis is the first oncologic symptom.

Case report: A 42-year-old woman with a hard, well-defined nodule situated anteriorly in the right orbit and with mild associated inflammation. MR showed an oval image with homogeneous gadolinium uptake. On excision-biopsy a ductal cancer was found and determined on CAT scan to be of pulmonary origin. Chemotherapy was given and no recurrence occurred in the orbit.

Conclusion: Ophthalmologic examination was the first step in the diagnosis of a metastasis of adenocarcinoma of the lung.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary*
  • Adult
  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Biopsy
  • Cisplatin / administration & dosage
  • Cisplatin / therapeutic use
  • Deoxycytidine / administration & dosage
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Gadolinium
  • Gemcitabine
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / diagnostic imaging
  • Magnetic Resonance Imaging
  • Orbit / pathology
  • Orbital Neoplasms / diagnosis
  • Orbital Neoplasms / drug therapy
  • Orbital Neoplasms / pathology
  • Orbital Neoplasms / secondary*
  • Radiography, Thoracic
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents
  • Deoxycytidine
  • Gadolinium
  • Cisplatin
  • Gemcitabine