Biotransformation of 6,7-epoxygeraniol by fungi

Appl Microbiol Biotechnol. 2005 Aug;68(3):311-5. doi: 10.1007/s00253-004-1886-x. Epub 2005 Jan 27.

Abstract

The biotransformation of 6,7-epoxygeraniol by resting cells of selected fungi was investigated. The main product obtained from the transformation in Rhodotorula glutinis and R. marina cultures was 6,7-epoxynerol (5-48% of chloroform extracts), whereas Saccharomyces cerevisiae, Candida parapsilosis and C. kefyr reduced this substrate to 6,7-epoxycitronellol (30-33% of chloroform extracts). Cultures of Yarrowia lipolytica, Botrytis cinerea and S. cerevisiae promoted the cyclisation of 6,7-epoxygeraniol to 2-methyl-2-(2-hydroxyethyl)-5-(2-hydroxyprop-2-yl)tetrahydrofuran (11-99% of chloroform extracts). The biotransformation of 6,7-epoxynerol was also investigated. However, none of the tested micro-organisms converted this compound.

MeSH terms

  • Acyclic Monoterpenes
  • Biotransformation
  • Epoxy Compounds / chemistry
  • Epoxy Compounds / metabolism*
  • Fungi / metabolism*
  • Terpenes / chemistry
  • Terpenes / metabolism*
  • Time Factors

Substances

  • Acyclic Monoterpenes
  • Epoxy Compounds
  • Terpenes
  • geraniol