Outcomes of hysterectomy in HIV-seropositive women compared to seronegative women

Infect Dis Obstet Gynecol. 2005 Sep;13(3):167-9. doi: 10.1080/10647440500147901.

Abstract

Objective: To compare the postoperative complication rates after hysterectomy between HIV-infected patients and HIV-uninfected patients.

Study design: We conducted a retrospective study of 24 human immunodeficiency virus-infected patients who underwent hysterectomy between January 1, 2000 and April 2, 2003 at Grady Memorial Hospital. Postoperative complications rates among HIV-infected women were compared to those rates among HIV-uninfected women. Data were analyzed t-tests for continuous variables and chi-squared tests for categorical variables.

Results: The HIV-infected women were more likely to report smoking and recreational drug use. In addition, a higher proportion of the HIV-infected women were co-infected with hepatitis, with more than one-quarter of HIV-infected women being hepatitis B or C seropositive. Although the study was limited due to small sample size, no significant differences in complication rates were found among HIV-infected women compared with uninfected women.

Conclusion: As HIV-infected women are living longer, healthier lives we anticipate that increased numbers of HIV-infected women will be undergoing hysterectomy for benign gynecologic conditions. It will be important, therefore, to carefully document any potential differences in operative risks.

MeSH terms

  • Adult
  • CD4 Lymphocyte Count
  • Female
  • HIV Infections / complications
  • HIV Seropositivity / complications*
  • Hepatitis B / complications
  • Hepatitis C / complications
  • Humans
  • Hysterectomy*
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome*