Pentasaccharide glycosides from the roots of Ipomoea murucoides

J Nat Prod. 2005 Aug;68(8):1141-6. doi: 10.1021/np050075m.

Abstract

Five pentasaccharide glycosides, murucins 1-5 (1-5), were isolated from the roots of the arboreal species Ipomoea murucoides, and their structures were elucidated by spectroscopic and chemical methods. Compounds 1-5 were evaluated for cytotoxicity against a small panel of cancer cell lines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Carbohydrate Sequence
  • Drug Screening Assays, Antitumor
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Humans
  • Ipomoea / chemistry*
  • Mexico
  • Molecular Structure
  • Oligosaccharides / chemistry
  • Oligosaccharides / isolation & purification*
  • Oligosaccharides / pharmacology
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Glycosides
  • Oligosaccharides