SPK-843 (Aparts/Kaken)

Curr Opin Investig Drugs. 2005 Aug;6(8):845-53.

Abstract

SPK-843 is a water-soluble antibiotic under co-development by Aparts and Kaken for the potential treatment of systemic fungal infections. By November 2004, SPK-843 was in phase II trials for systemic mycosis.

Publication types

  • Review

MeSH terms

  • Animals
  • Antifungal Agents / metabolism
  • Antifungal Agents / pharmacokinetics
  • Antifungal Agents / pharmacology*
  • Antifungal Agents / therapeutic use*
  • Antifungal Agents / toxicity*
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Humans
  • Mycoses / drug therapy*
  • Mycoses / microbiology
  • Patents as Topic
  • Polyenes / metabolism
  • Polyenes / pharmacokinetics
  • Polyenes / pharmacology*
  • Polyenes / therapeutic use*
  • Polyenes / toxicity*
  • Structure-Activity Relationship

Substances

  • Antifungal Agents
  • Polyenes
  • SPA S 843