[Experimental study on antidiabetic effect of the total flavonoids in Leucaena seeds]

Zhongguo Zhong Yao Za Zhi. 2005 Jun;30(11):842-4.
[Article in Chinese]

Abstract

Objective: To study the hypoglycemic effect of the total flavonoids in Leucaena seeds(TF).

Method: Experimental observation was performed by using various diabetic mice induced by alloxan, adrenalin, etc.

Result: TF could significantly lower the blood glucose levels in Alloxan model mice, adrenalin model mice and hyperglycemic mice, while had no hypoglycemic effect on the normal mice.

Conclusion: The total flavonoids in Leucaena seeds has hypoglycemic effect in diabetic model mice.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Glucose / metabolism*
  • Diabetes Mellitus, Experimental / blood*
  • Epinephrine
  • Fabaceae / chemistry*
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology*
  • Hyperglycemia / blood
  • Hyperglycemia / chemically induced
  • Hypoglycemic Agents / isolation & purification
  • Hypoglycemic Agents / pharmacology*
  • Male
  • Mice
  • Plants, Medicinal / chemistry
  • Seeds / chemistry

Substances

  • Blood Glucose
  • Flavonoids
  • Hypoglycemic Agents
  • Epinephrine