Identification of a novel human DRB1*13 allele by sequence-based DRB typing

Tissue Antigens. 2005 Sep;66(3):246-7. doi: 10.1111/j.1399-0039.2005.00451.x.

Abstract

Herein, we report on a novel DRB1 allele (DRB1*1368) identified during sequence-based HLA-DRB typing. This new DRB1 allele is identical to DRB1*1301 at exon 2 except for a single-nucleotide substitution at codon 37, changing the amino acid Asn to Asp.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles*
  • Base Sequence
  • Exons
  • Female
  • HLA-DR Antigens / genetics*
  • HLA-DRB1 Chains
  • Histocompatibility Testing
  • Humans
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • HLA-DR Antigens
  • HLA-DRB1 Chains
  • HLA-DRB1*13 antigen

Associated data

  • GENBANK/AY963587