Abstract
We have previously reported that the respiratory pathogen Bordetella bronchiseptica can form biofilms in vitro. In this report, we demonstrate the disruption of B. bronchiseptica biofilms by rhamnolipids secreted from Pseudomonas aeruginosa. This suggests that biosurfactants such as rhamnolipids may be utilized as antimicrobial agents for removing Bordetella biofilms.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology
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Biofilms / drug effects*
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Biofilms / growth & development
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Bordetella bronchiseptica / drug effects*
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Bordetella bronchiseptica / growth & development
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Colony Count, Microbial
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Glycolipids / isolation & purification
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Glycolipids / pharmacology*
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Pseudomonas aeruginosa / chemistry*
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Staining and Labeling
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Surface-Active Agents / isolation & purification
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Surface-Active Agents / pharmacology
Substances
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Anti-Bacterial Agents
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Glycolipids
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Surface-Active Agents
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rhamnolipid