Characterization of p30, a highly antigenic membrane and secreted protein of African swine fever virus

C L Afonso; C Alcaraz; A Brun; M D Sussman; D V Onisk; J M Escribano; D L Rock

doi:10.1016/0042-6822(92)90718-5

Characterization of p30, a highly antigenic membrane and secreted protein of African swine fever virus

Virology. 1992 Jul;189(1):368-73. doi: 10.1016/0042-6822(92)90718-5.

Authors

C L Afonso¹, C Alcaraz, A Brun, M D Sussman, D V Onisk, J M Escribano, D L Rock

Affiliation

¹ Plum Island Animal Disease Center, United States Department of Agriculture, Greenport, New York 11944.

PMID: 1604821
DOI: 10.1016/0042-6822(92)90718-5

Abstract

We have identified and characterized a 30-kDa phosphoprotein (p30) of African Swine Fever Virus (ASFV) that is synthesized, membrane localized, and released into the culture medium at early times after infection. Sequence analysis of the p30 open reading frame predicts a highly antigenic protein with putative phosphorylation, glycosylation, and membrane attachment sites.

MeSH terms

African Swine Fever Virus / genetics*
African Swine Fever Virus / immunology
Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antigens, Viral / biosynthesis
Antigens, Viral / genetics*
Antigens, Viral / immunology
Base Sequence
Cells, Cultured
Glycosylation
Macrophages / microbiology
Membrane Proteins / genetics
Membrane Proteins / immunology
Membrane Proteins / metabolism
Molecular Sequence Data
Phosphoproteins / genetics*
Phosphoproteins / immunology
Phosphoproteins / metabolism
Phosphorylation
Protein Conformation
Swine
Viral Proteins / genetics*
Viral Proteins / immunology
Viral Proteins / metabolism

Substances

Antibodies, Monoclonal
Antigens, Viral
Membrane Proteins
Phosphoproteins
Viral Proteins
P30 protein, African Swine Fever Virus

Associated data

GENBANK/M88336