Snail peptide expression pattern in the nervous system of the medicinal leech

Nikolay Aseyev; Viktor Ierusalimsky; Dmitry Boguslavsky; Pavel Balaban

doi:10.1016/j.molbrainres.2005.06.012

Snail peptide expression pattern in the nervous system of the medicinal leech

Brain Res Mol Brain Res. 2005 Oct 31;140(1-2):99-105. doi: 10.1016/j.molbrainres.2005.06.012. Epub 2005 Jul 20.

Authors

Nikolay Aseyev¹, Viktor Ierusalimsky, Dmitry Boguslavsky, Pavel Balaban

Affiliation

¹ Institute of Higher Nervous Activity and Neurophysiology, 5A Butlerova Street, Moscow 117485, Russia.

PMID: 16039008
DOI: 10.1016/j.molbrainres.2005.06.012

Abstract

Distribution of neurons immunopositive to antibodies against the "command neuron peptides" (CNPs) encoded by the snail Helix Command-Specific 2 (HCS2) gene was investigated in the nervous system of medicinal leech Hirudo. Immunopositive neurons were found in the leech segmental ganglia, brain and tail ganglionic masses, and peripheral ganglia. The CNPs immunopositive fibers were observed in neuropils of all ganglia and in some nerves. The role of CNPs immunopositive cells in animal behavior and the putative functions of the CNPs neuropeptide family are discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Calcium-Binding Proteins / genetics*
Gene Expression Regulation*
Immunohistochemistry
Interneurons / physiology*
Leeches / genetics*
Nervous System Physiological Phenomena*
Neuropeptides / genetics*
Snails / genetics*

Substances

Calcium-Binding Proteins
HCS2 protein, Helix lucorum
Neuropeptides