Effects of carbachol and adenosine on neurotransmitter secretion induced by potassium chloride, ionomycin, and sucrose

Bull Exp Biol Med. 2005 Feb;139(2):193-5. doi: 10.1007/s10517-005-0245-y.
[Article in English, Russian]

Abstract

We compared the effects of adenosine and cholinergic agonist carbachol on spontaneous secretion during local application of K+, ionomycin, and sucrose increasing Ca2+ concentration in the nerve terminal. Adenosine and carbachol had no effect on Ca2+ entry, but modulated later stages of exocytosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine / pharmacology*
  • Animals
  • Carbachol / pharmacology*
  • Exocytosis / drug effects*
  • Ionomycin / pharmacology
  • Muscle, Skeletal / cytology
  • Neuromuscular Junction / drug effects*
  • Neuromuscular Junction / metabolism
  • Neurotransmitter Agents / metabolism*
  • Potassium Chloride / pharmacology
  • Rana ridibunda
  • Sucrose / pharmacology
  • Synaptic Transmission / drug effects

Substances

  • Neurotransmitter Agents
  • Ionomycin
  • Sucrose
  • Potassium Chloride
  • Carbachol
  • Adenosine