The purpose of this study was to compare the retention force of FRC posts which were built up using direct and direct-indirect fabrication techniques with two fiber-reinforced core build-up systems (FibreKor and i-TFC). Posts were cemented in endodontically treated bovine single roots with resin cement using either direct or direct-indirect technique. Following which, the retention force of post-and-cores and fracture sites were examined. It was found that both the retention force and fracture site depended on the fabrication technique and resin cements. Post-and-cores built up with direct-indirect technique had greater retention force than those fabricated using direct technique. Fracture modes most frequently observed were adhesive failure at Resin/Dentin interface, a mixture of adhesive failures at Post/Resin and Resin/Dentin interfaces as well as cohesive failure of resin cements. Based on the results of this study, we concluded that when it comes to post-and-core build-up for endodontically treated tooth, the direct-indirect technique is more effective than the direct technique on the retention force of FRC posts.