A comparison of the COG and MCNP codes in computational neutron capture therapy modeling, Part I: boron neutron capture therapy models

Health Phys. 2005 Aug;89(2):127-34. doi: 10.1097/01.hp.0000160544.76255.78.

Abstract

The goal of this study was to evaluate the COG Monte Carlo radiation transport code, developed and tested by Lawrence Livermore National Laboratory, for neutron capture therapy related modeling. A boron neutron capture therapy model was analyzed comparing COG calculational results to results from the widely used MCNP4B (Monte Carlo N-Particle) transport code. The approach for computing neutron fluence rate and each dose component relevant in boron neutron capture therapy is described, and calculated values are shown in detail. The differences between the COG and MCNP predictions are qualified and quantified. The differences are generally small and suggest that the COG code can be applied for BNCT research related problems.

Publication types

  • Comparative Study
  • Evaluation Study
  • Validation Study

MeSH terms

  • Body Burden
  • Boron Neutron Capture Therapy / methods*
  • Computer Simulation
  • Humans
  • Models, Biological*
  • Neoplasms / physiopathology*
  • Neoplasms / radiotherapy*
  • Radiometry / methods*
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy, Computer-Assisted / methods*
  • Relative Biological Effectiveness
  • Software Validation
  • Software*
  • Treatment Outcome