Fatal pulmonary infection in a leukaemic patient caused by Hormographiella aspergillata

J Med Microbiol. 2005 Jul;54(Pt 7):685-688. doi: 10.1099/jmm.0.46016-0.

Abstract

A case of autopsy-proven fungal pneumonia in a relapsed leukaemia patient is reported. The fungus Hormographiella aspergillata was cultured from two bronchoalveolar fluid samples and identified through morphological examination and ITS2 sequence analysis. In addition, galactomannan was detected in eight consecutive serum samples, which suggested a co-infection with Aspergillus species. The patient was treated with caspofungin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Agaricales / classification*
  • Agaricales / genetics
  • Agaricales / isolation & purification
  • Aspergillosis / complications*
  • Aspergillosis / diagnosis
  • Bronchoalveolar Lavage Fluid / microbiology
  • Coprinus / classification
  • Coprinus / isolation & purification
  • DNA, Intergenic / chemistry
  • Fatal Outcome
  • Galactose / analogs & derivatives
  • Humans
  • Leukemia, Myelomonocytic, Acute / complications*
  • Lung / diagnostic imaging
  • Lung / microbiology
  • Lung Diseases, Fungal / diagnosis
  • Lung Diseases, Fungal / microbiology*
  • Male
  • Mannans / blood
  • Tomography, X-Ray Computed

Substances

  • DNA, Intergenic
  • Mannans
  • galactomannan
  • Galactose