DNA-coated microcrystals

Chem Commun (Camb). 2005 Jun 7:(21):2675-6. doi: 10.1039/b501045d. Epub 2005 Apr 20.

Abstract

Coprecipitation leads to self-assembly of bioactive DNA on the surface of salt, sugar or amino-acid crystals and provides a rapid inexpensive immobilization method suitable for preparing dry-powder formulations of nucleic acids, useful for storage, imaging and drug delivery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2-Propanol / chemistry
  • Chemical Precipitation
  • Crystallization
  • DNA / chemistry*
  • DNA / genetics
  • Green Fluorescent Proteins / genetics
  • HeLa Cells
  • Humans
  • Microchemistry
  • Microscopy, Confocal
  • Microscopy, Electron, Scanning
  • Microscopy, Fluorescence
  • Particle Size
  • Surface Properties
  • Transfection
  • Valine / chemistry*

Substances

  • Green Fluorescent Proteins
  • DNA
  • Valine
  • 2-Propanol