Detection of qnr in clinical isolates of Escherichia coli from Korea

Antimicrob Agents Chemother. 2005 Jun;49(6):2522-4. doi: 10.1128/AAC.49.6.2522-2524.2005.

Abstract

qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / pharmacology
  • Drug Resistance, Bacterial / genetics*
  • Escherichia coli / drug effects
  • Escherichia coli / genetics*
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Proteins / genetics*
  • Humans
  • Integrons / genetics
  • Korea
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Quinolones / pharmacology
  • Sequence Analysis, DNA

Substances

  • Anti-Infective Agents
  • Escherichia coli Proteins
  • Qnr protein, E coli
  • Quinolones

Associated data

  • GENBANK/AY878717
  • GENBANK/AY878718