The long-term effect of physical activity on incidence of coronary heart disease: a 12-year follow-up study

Prev Med. 2005 Jul;41(1):219-25. doi: 10.1016/j.ypmed.2004.09.043. Epub 2004 Dec 9.

Abstract

Background: This study analyzed the long-term effect of leisure-time physical activity on incident cases of coronary heart disease (CHD) among women and men.

Methods: A national, random sample of 2,551 women and 2,645 men, aged 35-74, was interviewed in 1988 and 1989 and followed until December 31, 2000, with respect to CHD incident cases. Women and men hospitalized for CHD 2 years before the start of the study and those who rated their general health as poor were not included in the sample. Leisure-time physical activity was divided into four levels according to the frequency of physical activity. The relationship between leisure-time physical activity and CHD was studied in a Cox regression model, adjusted for sex, age, income, smoking, and BMI.

Results: When leisure-time physical activity increased, the risk of CHD decreased. Women and men who were physically active at least twice a week had a 41% lower risk of developing CHD than those who performed no physical activity (hazard ratio = 0.59, CI = 0.37-0.95), after adjustment for all the explanatory variables.

Conclusions: The positive long-term effect of leisure-time physical activity on CHD risk among women and men remains even after accounting for income and other important CHD risk factors.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Cohort Studies
  • Confidence Intervals
  • Coronary Disease / epidemiology*
  • Coronary Disease / prevention & control*
  • Exercise / physiology*
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Physical Fitness / physiology*
  • Proportional Hazards Models
  • Risk Assessment
  • Sex Distribution
  • Survival Analysis
  • Sweden / epidemiology
  • Time Factors