Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium

E Attard; M P Brincat; A Cuschieri

doi:10.1016/j.fitote.2005.02.007

Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium

Fitoterapia. 2005 Jul;76(5):439-41. doi: 10.1016/j.fitote.2005.02.007.

Authors

E Attard¹, M P Brincat, A Cuschieri

Affiliation

¹ Institute of Agriculture, University of Malta, Malta. everaldo.attard@um.edu.mt

PMID: 15908139
DOI: 10.1016/j.fitote.2005.02.007

Abstract

The immunomodulatory effect of cucurbitacin E, extracted from Ecballium elaterium, was tested on peripheral human lymphocytes. These lymphocytes were co-cultured with cancer cells and an interesting lymphocyte-mediated cytotoxicity was observed.

MeSH terms

Cell Line, Tumor
Cucurbitaceae*
Female
Humans
Immunologic Factors / administration & dosage
Immunologic Factors / pharmacology*
Immunologic Factors / therapeutic use
Lymphocytes / drug effects*
Male
Phytotherapy*
Triterpenes / administration & dosage
Triterpenes / pharmacology*
Triterpenes / therapeutic use

Substances

Immunologic Factors
Triterpenes
cucurbitacin E