Indicators for post-surgery recovery in Mongolian gerbils (Meriones unguiculatus)

Lab Anim. 2005 Apr;39(2):200-8. doi: 10.1258/0023677053739828.

Abstract

Telemetric investigations of various parameters are widely used to estimate an animal's state. However, the implantation of the transmitters includes anaesthesia and surgery and has short and longer lasting impacts on the studied object. The aim of the present paper was to evaluate these effects in Mongolian gerbils, namely the hypothermia caused by the anaesthetic and the enduring disturbance of daily rhythmicity until complete recovery. The surgery associated with the implantation of the transmitters differed both in severity and type of anaesthesia. Whereas normal values of body temperature were restored within hours, restoration of daily rhythm required several days, depending on the severity of the surgical procedure. Also, the sensitivity of the body temperature to activity changes was different until the rhythms were re-established. A method based on the rhythm magnitude and shape was proposed to estimate the time until complete recovery of the animals.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anesthetics, Inhalation / adverse effects*
  • Animals
  • Body Temperature Regulation / drug effects
  • Circadian Rhythm / drug effects*
  • Female
  • Gerbillinae / physiology*
  • Gerbillinae / surgery*
  • Hypothermia / chemically induced*
  • Male
  • Telemetry / methods*

Substances

  • Anesthetics, Inhalation