[New syntheses of alpha-methyl- and alpha,alpha'-dimethylspermine]

N A Grigorenko; J Vepsalainen; A Jarvinen; T A Keinanen; L Alhonen; J Janne; A R Khomutov

doi:10.1007/s11171-005-0025-5

[New syntheses of alpha-methyl- and alpha,alpha'-dimethylspermine]

Bioorg Khim. 2005 Mar-Apr;31(2):200-5. doi: 10.1007/s11171-005-0025-5.

[Article in Russian]

Authors

N A Grigorenko, J Vepsalainen, A Jarvinen, T A Keinanen, L Alhonen, J Janne, A R Khomutov

PMID: 15889795
DOI: 10.1007/s11171-005-0025-5

Abstract

alpha-Methylspermine and alpha,alpha'-dimethylspermine were synthesized in high overall yields starting from N-(benzyloxycarbonyl)-3-aminobutanol in order to study polyamine biochemistry in vitro and in vivo.

Publication types

English Abstract

MeSH terms

Magnetic Resonance Spectroscopy / methods
Spermine / analogs & derivatives*
Spermine / chemical synthesis*
Spermine / chemistry
Stereoisomerism

Substances

alpha-methylspermine
1,12-dimethylspermine
Spermine