Ventriculoperitoneal shunt in patients with leptomeningeal metastasis

Neurology. 2005 May 10;64(9):1625-7. doi: 10.1212/01.WNL.0000160396.69050.DC.

Abstract

The authors reviewed 37 patients with leptomeningeal metastasis (LM) who required a ventriculoperitoneal shunt (VP shunt) for management of intracranial hypertension. Improvement was seen in 27 (77%) patients; subdural hematoma developed in one and shunt malfunction in three. Median overall survival was 2 months (range 2 days to 3.6 years) after VP shunt placement, but there was no procedure-related mortality. The prognosis of LM remained poor, but VP shunt can be an effective palliative tool when required.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain / pathology
  • Brain / physiopathology
  • Brain Neoplasms / secondary
  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy
  • Carcinoma / complications*
  • Carcinoma / secondary
  • Female
  • Humans
  • Hydrocephalus / etiology
  • Hydrocephalus / physiopathology
  • Hydrocephalus / surgery
  • Intracranial Hypertension / etiology
  • Intracranial Hypertension / physiopathology
  • Intracranial Hypertension / surgery*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy
  • Magnetic Resonance Imaging
  • Male
  • Meningeal Neoplasms / complications*
  • Meningeal Neoplasms / secondary
  • Middle Aged
  • Neoplasm Metastasis / pathology
  • Neoplasm Metastasis / physiopathology*
  • Palliative Care / standards
  • Palliative Care / trends
  • Prognosis
  • Subarachnoid Space / pathology
  • Subarachnoid Space / physiopathology
  • Subarachnoid Space / surgery*
  • Survival Rate
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ventriculoperitoneal Shunt / standards*
  • Ventriculoperitoneal Shunt / trends